A complete guide to needle-free pens from NAD+ At Home.
When it comes to wellness and biohacking, NAD+ has firmly established itself as the must-have supplement for those seeking greater energy, sharper focus, and better ageing from the inside out.
You’ve probably heard the likes of Hailey Bieber, Kendall Jenner, Jennifer Aniston, Justin Bieber, Joe Rogan, and many more well-known names swearing by NAD+ IV drips. But what if you could get all the same benefits, without the hassle of clinical appointments or needle fear – and in the comfort of your own home?
We’d like to introduce you to our newest addition, the NAD+ Pen. It’s a sleek, needle-free device that allows you to self-administer NAD+ at home in seconds. No fuss. No needles. No pain.
In this guide, we’ll explore what the NAD+ injection pen is, how it works, why it’s a game-changer, and how to use it safely, so you can decide if it’s right for your wellness routine. For a slightly more traditional administration, check out our NAD Injection Kit.
What’s NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every single cell in your body. It plays a key role in:
- – Energy metabolism (converting food into fuel).
- – DNA repair
- – Cell regeneration
- – Brain function
- – Ageing processes
Here’s the kicker, though – your natural NAD+ levels decline with age. By the time you reach your 40s or 50s, NAD+ production can be up to 50% lower than in your youth. This dip is linked to fatigue, brain fog, sluggish metabolism, and visible signs of ageing.
That’s why NAD+ supplementation has exploded in popularity, especially via injections, which can offer superior bioavailability.


Traditional NAD+ Injections: The Problem
If you wanted to opt for NAD+ injections, until now, that typically meant either:
- – Booking a clinic or home visit for an IV drip or intramuscular injection.
- – Using a needle, which for some people can be uncomfortable or intimidating
- – Paying high costs for each appointment
While all very effective, we understand that these methods just aren’t practical or accessible for everyone, especially if you’re needle-averse or want to maintain your own protocol regularly at home.
So, we’ve created an alternative solution.
What Makes The Pen Different?
We like to think of it as a wellness upgrade. This innovative device allows you to inject NAD+ subcutaneously without the use of a traditional needle.
It’s inspired by insulin pens, but purpose-built for NAD+ delivery.
Here’s what sets it apart:
- – No appointments or clinic visits
- – Small, fine needle for ease of use
- – No stress around timing or access
- – No mess or measuring
Just fast, precise, painless supplementation that fits seamlessly into your day.
How Our Injection Pen Works
Instead of a needle, the pen uses auto-injector technology to deliver the NAD+ just under the skin. It’s:
- – Virtually painless
- – Extremely precise
- – Quick and simple to use
- – Designed for home use
You’ll receive everything you need. The pen, pre-measured cartridges, and easy instructions help you start your NAD+ protocol confidently and safely.


What’s Included?
When you order your NAD+ Injection Pen, you’ll receive everything you need to start confidently:
- – The reusable NAD+ Pen device
- – Pre-filled NAD+ cartridges for simple dosing
- – Step-by-step instructions
- – A free travel case with cold packs for storage and portability
No complicated setup. No separate supplies. Just open the box, follow the guide, and you’re ready to go!
6 Key Benefits:
1. Fine Needle Tip for a Gentle Experience
Uses a very fine needle, similar to an insulin pen, for a quick and nearly painless injection. Designed for comfort and ideal even if you’re usually not a fan of needles!
2. On-Demand Convenience
Use it anytime, anywhere. At home, while travelling, or even in the office. It takes quite literally under 60 seconds to administer.
3. Enhanced Bioavailability
Subcutaneous delivery offers a more direct route into the bloodstream, which can support faster and more efficient absorption compared to other methods like oral or topical formats.
So, although capsules are a convenient option for daily use, injections may be preferred for those seeking rapid, targeted effects!
4. Precision Dosing
Each cartridge is pre-filled to ensure you’re getting the exact right amount every time, no guesswork, no wastage.
5. Cost-Effective Long-Term
Compared to regular clinic-based NAD+ therapy, the pen saves you money, especially for ongoing use.
6. Discreet and Travel-Friendly
Lightweight and compact, the pen slips easily into your bag or drawer.
What Sort Of Results Can You Expect?
Many of our customers have reported noticeable improvements within days or weeks of starting a NAD+ protocol. Benefits may include:
- – More consistent energy throughout the day
- – Sharper memory and cognitive function
- – Better mood and resilience to stress
- – Improved athletic performance and recovery
- – Enhanced skin elasticity and appearance
- – Slower signs of ageing on a cellular level
Results vary person to person, and the key is consistency; that’s where the ease of using an injection pen really shines.

Who’s It For?
The NAD+ Injection Pen is designed for people who want more out of every day. More clarity, more energy, more longevity.
It’s perfect for:
- – High performers seek a mental and physical edge to stay sharp and energised.
- – Wellness enthusiasts focused on ageing well and living vibrantly.
- – Biohackers who prioritise precision and efficiency in their routines
- – Athletes and active individuals looking to support faster recovery and sustained endurance.
- – Adults 35+ are ready to proactively support their NAD+ levels as they age.
Whether you’re just starting your NAD+ journey or looking for a way to improve your existing routine, we’ve designed our NAD+ Injection Pen Kits to offer a seamless, consistent way to elevate your wellness on your schedule.

Step By Step Usage Guide:
Using the NAD+ Injection Pen is simple and straightforward:
- Clean the skin (abdomen or outer thigh works best)
- Load your cartridge into the pen following the guide provided
- Prime the pen by pressing once to prepare the dose
- Place against the skin and press the button to administer
- Dispose of used cartridges in a sharps bin or as instructed
That’s it. You’re done in under a minute. We’ve made a more in-depth guide on how to use the NAD+ Injection Pen for those who want extra confidence or are using it for the first time.

Final Thoughts: Should You Try Our NAD+ Pen?
If you’re looking to boost your energy, support brain function, and age smarter, the NAD+ Injection Pen offers a way to do so safely, easily, and on your own terms.
It brings together the science of cellular health and the convenience of modern wellness technology, without compromising on results. So, are you:
- – Ready to take control of your health?
- – Curious to experience the benefits of NAD+?

The NAD+ Injection Pen: FAQS
There’s been a lot of excitement with this launch, so naturally, we’ve received a lot of questions and queries about the NAD+ Pen.
We’ve answered the most frequently asked questions below!
Does it hurt?
Most users report minimal to zero discomfort, much less than a traditional injection or blood draw.
How fast will I feel results?
Some people notice improved energy and focus within days, while others feel gradual benefits over 2 to 4 weeks.
How often should I use it?
That really depends on you!
We typically recommend starting with one dose per day for the first three days, as this helps kickstart your system. After that, most people switch to every other day or 1–2 times per week, depending on how they feel.
Listen to your body. Everyone’s NAD+ needs are different, which is why some people thrive on daily doses, while others do best with just a couple per week.
Can I travel with it?
Yes! Our NAD pen is portable, and the cartridges can be carried easily. Plus, you get a free travel case with cold cooler packs. Just check airline rules for liquid medications and injection devices.
In recent decades, modern life has transformed dramatically, bringing with it a wide range of challenges for our heath and wellbeing. From environmental toxins and oxidative stress to processed foods and chronic inflammation, there are plenty of new-world health risks which may be increasing cellular ageing and depleting our body’s reserves of important natural molecules and nutrients.
Fortunately, there’s plenty of promising research into NAD+ supplementation and how it may play a role in halting or even reversing cellular ageing, while more generally improving the efficiency of our biological functions.
Although NAD+ injections and IV therapy are the most proven methods for increasing NAD+ within our bodies, NAD+ capsules have a come long way, too.
The key is the use of liposomes and liposomal technology to ensure much need nutrients arrive at our cells unharmed and ready to make an impact.
Here, we’ll explore exactly what Liposomal NAD+ is and how liposomes (particularly our SAIFx® technology) help maximise the bio-availability and efficiency of NAD+ within our bodies.
What is Liposomal NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme essential to every living cell in your body. This molecule plays a role in hundreds of bodily processes, from energy production in our mitochondria to DNA repair and cellular regeneration.
Unfortunately, by the time we reach middle age, studies have shown NAD+ levels drop to approximately half those of available in our younger days, a decline that correlates with the onset of many age-related concerns.
What are liposomes?
Liposomes are like a microscopic version of an Uber Eats driver! They help our bodies move nutrients around, particularly allowing our cells to receive the molecules they require for a whole host of bodily functions.
For those of a more scientific background, liposomes are “spherical vesicles composed of phospholipids” and are the same molecules that form our cell membranes. We’ll explore this in a little more detail but for the full lowdown, check out our guide to what liposomal means.
These intelligent units house active ingredients and shield them from the harsh acidic environment of digestive system, enabling absorption into your bloodstream and cells.
As per naitre.com, “liposomes are spheres made of a dual lipid bilayer with an aqueous core where the active ingredients are held. They can be made in the laboratory starting from naturally derived lipids such as phosphatidylcholine-enriched lipids. This means that they will have minimal toxicity since the body won’t recognised them as “foreign” agents.”
While it’s all quite scientific, there are some important advantages of using liposomes for drug delivery, also reported by naitre.com:
1. Enhanced uptake and bioavailability
2. Biocompatibility
3. Biodegradability
4. Low toxicity
5. Possibility to tailer target-specific delivery
The Science Behind Our SAIFx® Encapsulation Technology
Oral supplements face a host of challenges when travelling through your digestive system. Many nutrients that supplements are supposed to increase get broken down by acid in the stomach or metabolised by the liver before reaching their target. Simply, the harsh environments of our stomach can reduce the efficacy of supplements which are ingested without protective measures.
That’s why liposomal technology is important. By improving the delivery of supplements, we can protect the active ingredients of supplements as they pass through the stomach and into the intestines.

Put simply, this increases the bio-availability of active ingredients and helps ensure they reach their required destination, in as close to full strength as possible, ready to play their role in improving our health. As shown below, liposomes attach to your cell membrane and allow the active ingredient they contain to be fully ingested by the cell it targets.
Bioavailability studies have shown liposomal supplements demonstrate up to 46 times greater bioavailability compared to non-liposomal alternatives. This dramatic difference means your body can actually utilise what you’re taking, rather than simply passing it through your system.
It’s worth noting here that liposomes aren’t anything new. In fact, the body naturally transports NMN (a key NAD+ precursor) through the bloodstream using extracellular vesicles that are themselves liposomes.
Liposomal NAD+, therefore, may mimic the body’s own transport system, enhancing uptake and working alongside your body’s natural processes.

The potential benefits of NAD+ supplementation
So, now we know how liposomal technology can improve the efficiency of supplements, let’s explore how NAD+ may impact our overall health.
First, it’s important to raise that while scientific evidence for the benefits of NAD+ supplementation continues to increase, more studies and clinical trials are required to truly determine its impact on our health and wellbeing. The potential benefits shared below are just that: potential and as yet unproven. However, what has so far been tested, in both animal and human trials, is promising and shows potential for:
1. Increased cellular energy
NAD+ plays a key role in energy production. It’s an essential part of how our mitochondria convert nutrients into ATP, a molecule that acts as the main energy currency for cells in living organisms. Users of NAD+ regularly report sustained energy throughout the day without the crashes typically associated with other energy sources, such as caffeine and other stimulants.
2. Improved metabolic health
NAD+ supplementation has been shown to boost insulin sensitivity, reverse mitochondrial dysfunction and support healthy metabolic function. These improvements help your body process nutrients more efficiently. Read our article to learn more about the role of NAD+ on metabolic health.
3. Better cognitive support and brain function
Increasing levels of NAD+ has shown significant neurological benefits in numerous animal trials. While more research is required, particularly on the impact to the human biological makeup, those animal studies show positive signs for cognition and nerve regeneration. What’s more, we often see enhanced mental clarity and focus frequently reported as benefits of NAD+ treatments.
4. Increased cardiovascular health
The heart demands extraordinary amounts of cellular energy. NAD+ shows promise for cardiovascular support, with studies demonstrating that “decreased NAD+ levels lead to inadequate ATP production and increased susceptibility to heart failure.” As research continues, scientists are exploring how to best increase NAD+ levels to alleviate heart failure.
5. Healthy ageing
NAD+ is being explored heavily by science and health leaders due to its crucial nature for cellular processes like DNA repair and energy production, both linked to ageing. Studies in animals show promising results while human studies are ongoing.
Summary
Liposomal NAD+ may support your body at the cellular level. Whether you’re seeking to enhance your energy reserves, improve brain function, optimise metabolic health or invest in long-term vitality, liposomal NAD+ could provide the bioavailable nutrition your cells need to thrive.
When it comes to all things health, wellness, and anti-ageing, very few molecules have gained as much attention as NAD+. If you’re looking to improve energy levels, slow ageing, or support overall health, understanding the potential NAD is essential.
But what exactly is NAD, why is it so important for our bodies, and why is everyone in the health and wellness community talking about it?
This article covers everything you need to know about NAD. What it is, how it works, the benefits, how you can potentially boost your levels naturally and the difference between NAD+ pens, NAD+ injections, and NAD+ capsules.
What’s NAD+?
NAD (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell. It plays a big role in our energy production, DNA repair, and overall cellular function. In other words, without NAD, our bodies wouldn’t be able to function properly.
There are two main functions: energy production, DNA repair, and longevity.
✔ Energy production: NAD helps with converting the food we eat into energy. It helps mitochondria (the cells that generate the most energy) produce adenosine triphosphate (the cells that carry energy to our living cells), which fuels all bodily functions.
✔ DNA repair & longevity: NAD is required by enzymes called sirtuins, which can help with repairing damaged DNA and regulate ageing processes. Without adequate NAD, cells can become damaged and age faster.
What are NAD Levels?
When you hear someone talking about NAD levels, all they are referring to is the amount of nicotinamide adenine dinucleotide in the body.
These levels will naturally decline as we age, typically starting to decrease in our late 30s and then dropping more significantly after 40. However, there are many varying factors to consider which can speed up the decline of natural NAD levels, which include (but aren’t limited to!):
✔ Stress
✔ Poor diet
✔ Lack of exercise
✔ Excessive alcohol consumption
If you have low NAD levels, you may experience fatigue, a slower metabolism, cognitive decline, and faster ageing. So, maintaining or increasing NAD levels has been known to support energy, brain function, and overall health.


Why is NAD+ So Important?
NAD is essential because it supports:
✔ Energy production
✔ Brain function
✔ Healthy ageing
✔ Muscle function
✔ Immune system regulation
✔ Metabolism
Why Does NAD+ Decline with Age?
As we get older, our bodies go through lots (and lots) of changes. Unfortunately, one of them is a drop in NAD+ levels.
Our natural levels of NAD drop because the body starts making less of it whilst also breaking it down faster. Our cells rely on NAD+ for energy production and repair, but as we age, certain enzymes that consume NAD+ become more active. At the same time, our ability to create new NAD+ also slows down.
The body also has special molecules that help recycle NAD+, but with age, these systems become less efficient. And as NAD+ is important for keeping cells healthy, its reduction can lead to lower energy, slower metabolism, and a higher risk of age-related diseases.
What Are the Key Benefits of Having Healthy Levels of NAD+?
There are many clear benefits of making sure your body has healthy levels of NAD, but the main ones involve anti-ageing, increased energy levels, better brain health, improved metabolic function, and immune system support.

Muscle Recovery, Energy Production and Cellular Function
NAD is key in cellular metabolism, as it helps facilitate the conversion of nutrients into usable energy.
- – How it works: NAD acts as a coenzyme in metabolic reactions, helping transport electrons needed to generate adenosine triphosphate (ATP), the primary energy currency of the body.
- – Why it matters: ATP is essential for normal cell function, and without enough NAD, cellular energy production can decline. This may contribute to feelings of fatigue and reduced endurance.
NAD is also linked with muscle function and physical performance, particularly in relation to how cells generate energy and recover from exercise.
- – Our NAD levels play a role in ATP production, which is essential for muscle contraction and endurance.
- – Some studies suggest that NAD may be involved in muscle recovery processes after exercise.
Brain Health and Improved Cognitive Function
NAD is involved in multiple processes related to neurological function, and it participates in pathways that regulate neurotransmitter levels, which are essential for cognitive functions such as memory, focus, and our ability to learn.
Our brains are also susceptible to oxidative stress and DNA damage. NAD is a cofactor for the enzyme poly(ADP-ribose) polymerases (PARPs), which help repair damaged DNA in neurons.
Improved Metabolism Function, Cellular Repair and Anti-Ageing Abilities
Ageing is associated with a decline in NAD levels, which may contribute to reduced cellular efficiency. Here are just a few ways in which having healthy NAD levels improves the ageing process:
- – Activates sirtuins: NAD+ activates sirtuins, proteins which are directly linked to longevity and cellular repair.
- – Enhances DNA repair: Helps repair damaged DNA, reducing age-related decline.
- – Improves mitochondrial function: Supports energy production, reducing fatigue and cellular ageing.
- – Reduces inflammation: Lowers chronic inflammation, a main factor associated with ageing.
- – Supports brain health: Protects neurons, improving memory and cognitive function.
- – Boosts metabolism: Nad can enhance metabolic efficiency, which helps with weight management.
- – Increases stem cell function: Promotes tissue regeneration and repair.
Immune System Support and Inflammation Regulation
Optimal NAD levels have been linked to immune function and inflammatory responses:
- – White blood cell function: Some promising studies suggest that NAD-dependent pathways are involved in the activation of macrophages and other immune cells that help protect the body from infections.
- – Inflammatory Response: NAD may play a role in regulating inflammation through its impact on sirtuins and other enzymes involved in immune signalling.
Can You Boost NAD+ Levels Naturally?
There are a few ways we can potentially boost our levels of NAD naturally:
- – Exercise, in the form of high-intensity workouts, weight training, and endurance exercise, all have the potential to stimulate NAD production by promoting mitochondrial health.
- – Intermittent fasting can trigger cellular repair processes and boost NAD by stimulating sirtuins. So, going without food for 12-16 hours can increase NAD production.
- – Certain foods and maintaining a healthy diet over the long term can help naturally boost NAD levels.
- – Alcohol depletes our natural NAD levels, making cells less efficient at repairing themselves. So, avoiding excessive alcohol consumption is essential when it comes to making sure you’re able to keep your NAD levels consistent naturally.
Although there are several ways to support boosting NAD levels naturally, these strategies may not always provide a significant or consistent increase. Taking supplements may be the most effective route for those looking to more effectively and reliably boost NAD+ levels and show promising results.
NAD supplements offer a more direct and potent way to raise NAD+ levels, supporting overall cellular function and potentially providing benefits that lifestyle changes alone may not fully deliver.
Different Types of NAD+ Supplements
For individuals looking to support their NAD levels, there are several supplementation options available. The three most common methods are:
- – IV therapy
- – At-home injections
- – Liposomal tablets.
Each option has its own advantages and factors to consider, making it important to understand which approach may best suit your needs.
NAD+ IV Therapy
NAD IV therapy involves delivering NAD directly into the bloodstream through an intravenous (IV) drip. This method is typically administered in wellness clinics and under medical supervision.
NAD IV therapy benefits include:
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